BDBM50465675 CHEMBL4282828

SMILES COc1ccccc1NC(=O)Nc1cc(ccc1O)S(N)(=O)=O

InChI Key InChIKey=TYTZFKRSGVNIDM-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465675   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  7.30nMAssay Description:Inhibition of human CA12 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  23nMAssay Description:Inhibition of human CA9 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  255nMAssay Description:Inhibition of human CA1 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50465675(CHEMBL4282828)
Affinity DataKi:  951nMAssay Description:Inhibition of human CA2 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed