BDBM50466377 CHEMBL4279772
SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(F)c2)C(C)(C)C(=O)Nc2cc(ccn2)C#N)cc1
InChI Key InChIKey=DUHFUKXNEHGMID-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50466377
Affinity DataIC50: 16nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]-Digoxin from recombinant human GST-fused RORgammat LBD after 1 to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Transrepression of RORgammat in anti-CD3/CD28 stimulated C57BL/6 mouse CD4-positive T cells assessed as suppression of T cell differentiation to Th17...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORbeta LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Transrepression of recombinant human GAL4-DBD fused LXRalpha LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Transrepression of recombinant human GAL4-DBD fused LXRbeta LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]T0901317 from recombinant human GST-fused RORalpha LBD after 1 to 4 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair