BDBM50466747 CHEMBL4288312

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)[C@H]1CC[C@H](CSc2nc3ccccc3o2)CC1

InChI Key InChIKey=GDRHTUCOIKUXHE-MXVIHJGJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466747   

TargetSterol O-acyltransferase 1(Human)
Kowa

Curated by ChEMBL
LigandPNGBDBM50466747(CHEMBL4288312)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ACAT in human J774A.1 cells assessed as reduction in esterified-cholesterol accumulation after 18 hrs in presence of 25-hydroxycholeste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed