BDBM50468131 CHEMBL4277106
SMILES [H][C@@]12CCN(Cc3cc(OCC)c(c(OCC)c3)-c3ccc(F)cc3)[C@]1([H])CCC2Nc1nc2ccc(cc2o1)C(O)=O
InChI Key InChIKey=VOZUDWOEAFDHSE-JNOFKKGSSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50468131
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at human SSTR1 expressed in CHO-K1 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of MK-499 binding to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair