BDBM50491557 CHEMBL2046886

SMILES CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c4nc5c(OCCCCN6CCN(CCn7ccnc7)CC6)cccc5oc4c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(=O)c2c(O)c3C

InChI Key InChIKey=BWDTVIVNIJMQGS-WQPMZEBSSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491557   

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50491557(CHEMBL2046886)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rifamycin-resistant Escherichia coli RNA polymerase D516V mutant after 10 mins by rolling circle transcription assay in presence of DNA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50491557(CHEMBL2046886)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of rifamycin-resistant Escherichia coli RNA polymerase S531L mutant after 10 mins by rolling circle transcription assay in presence of DNA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB