BDBM50491628 CHEMBL2386352
SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(c(CC(O)=O)c2c1)C(F)(F)F
InChI Key InChIKey=KDIVDXIRWHFVLU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50491628
Affinity DataKi: 1.30E+4nMAssay Description:Binding affinity to wild type human COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Inhibition of wild type human COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of wild type ovine COX1 expressed in ram seminal vesicles using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC fol...More data for this Ligand-Target Pair
Affinity DataIC50: 267nMAssay Description:Inhibition of wild type mouse COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 in human HNSCC1483 cells using [1-14C]-arachidonic acid as substrate assessed as inhibition of substrate oxygenation preincubated ...More data for this Ligand-Target Pair