BDBM50501234 CHEMBL3943318

SMILES Nc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1nc2cc(NS(=O)(=O)c3ccc(N)cc3)ccc2o1

InChI Key InChIKey=LCYYWRRGEZMPJO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50501234   

TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
Target60 kDa heat shock protein, mitochondrial(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of human mitochondrial HSP60/HSP10-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
Target60 kDa heat shock protein, mitochondrial(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of human mitochondrial HSP60/HSP10 expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human PTPN2 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human PTPN5 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged PtpB expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 30 mins by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human PTPN1 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli GroEL/ES-mediated refolding of the denatured malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Escherichia coli GroEL/ES-mediated refolding of the denatured rhodaneseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target60 kDa heat shock protein, mitochondrial(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human mitochondrial HSP60/10-mediated refolding of the denatured malate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetThiosulfate sulfurtransferase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50501234(CHEMBL3943318)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of refolded Rhodanese (unknown origin)-mediated conversion of cyanide to thiocyanate treated with compound after refolding of the denature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed