BDBM50503389 CHEMBL4452281

SMILES Cc1ccc(Nc2nccc(n2)-c2c(ncn2C2CCNCC2)-c2ccc(F)cc2)cc1C

InChI Key InChIKey=OGDBBVMMKPWVLG-UHFFFAOYSA-N

Data  4 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50503389   

TargetBromodomain testis-specific protein(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50503389(CHEMBL4452281)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human BRDT bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50503389(CHEMBL4452281)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain testis-specific protein(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50503389(CHEMBL4452281)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human BRDT bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50503389(CHEMBL4452281)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50503389(CHEMBL4452281)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)