BDBM50506039 CHEMBL1324296::US11891386, Compound 002

SMILES COC(=O)c1csc(n1)C(=O)c1c[nH]c2ccccc12

InChI Key InChIKey=KDDXOGDIPZSCTM-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50506039   

TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInterleukin-21(Homo sapiens (Human))
Ariagen

US Patent
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataIC50:  31.8nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-21(Homo sapiens (Human))
Ariagen

US Patent
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataIC50:  38.2nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]TCDD from mouse AhRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR in mouse Hepa2Dluc cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed