BDBM50511729 CHEMBL4589215

SMILES [H][C@@]1(c2ccccc2-c2cncn12)[C@]1([H])CCc2ccc(cc2[C@H]1O)P(C)(C)=O

InChI Key InChIKey=RJQCTYSBEJJLJK-BWAGFHJFSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511729   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511729(CHEMBL4589215)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of IDO1 in human A172 cells after 24 hrs in presence of IFNgamma by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511729(CHEMBL4589215)
Affinity DataEC50:  130nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511729(CHEMBL4589215)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed