BDBM50515771 CHEMBL4528047
SMILES Cc1nnc2CC[C@@H](Nc3ccc(Cl)cc3)c3cc(ccc3-n12)-c1cnn(C)c1
InChI Key InChIKey=MDRXOFSNECSECW-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50515771
TargetBromodomain-containing protein 2(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Binding affinity to human recombinant BRD2 BD2 (349 to 460 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 5.30nMAssay Description:Binding affinity to recombinant human BRD3 BD2 (306 to 417 residues) assessed as inhibition constant by fluorescence polarization binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Binding affinity to human recombinant BRD3 BD2 (306 to 417 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 7.30nMAssay Description:Binding affinity to human recombinant BRD4 BD2 (333 to 460 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Binding affinity to recombinant human BRD3 BD1 (24 to 144 residues) assessed as inhibition constant by fluorescence polarization binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Binding affinity to human recombinant BRD3 BD1 (24 to 144 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Binding affinity to human recombinant BRD4 BD1 (44 to 168 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Binding affinity to human recombinant BRD2 BD1 (72 to 205 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Binding affinity to human partial length BRD3 BD2 (G306 to P416 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 3nMAssay Description:Binding affinity to human partial length BRDT bromodomain 2 isoform b (K250 to E382 residues) expressed in bacterial expression system by bromoscan a...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 64nMAssay Description:Binding affinity to human partial length BRDT bromodomain 1 isoform b (N21 to E137 residues) expressed in bacterial expression system by bromoscan as...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 45nMAssay Description:Binding affinity to human partial length BRD2 BD1 isoform 1 (K71 to N194 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to human partial length BRD2 BD2 isoform 1 (E348 to D455 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 26nMAssay Description:Binding affinity to human partial length BRD4 BD1 isoform long (N44 to E168 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 3.5nMAssay Description:Binding affinity to human partial length BRD4 BD2 isoform long (K333 to E460 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human partial length BRD3 BD1 (P24 to E144 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair