BDBM50520176 CHEMBL4438389
SMILES Cc1noc(n1)-c1ccc2nc(Nc3cc(CN4CCN(CC(F)(F)F)CC4)ccn3)[nH]c2c1
InChI Key InChIKey=FZKOOFUVRBCBBS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50520176
Affinity DataIC50: 188nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.74E+3nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon/Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair