BDBM50521239 CHEMBL4443026

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1cc(Cl)ncn1)[C@H]2Nc1nc2N(CCCn2n1)c1ccc(C)c(F)c1

InChI Key InChIKey=KCZHRHIJVHZDHB-VPTLXERWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521239   

TargetPresenilin-1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50521239(CHEMBL4443026)
Affinity DataEC50:  0.0114nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed