BDBM50522305 CHEMBL4451159
SMILES Fc1ccc(cc1)S(=O)(=O)N1C(=O)NC(=O)C11CCCc2ccccc12
InChI Key InChIKey=HFXHDSJNJKVJNB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50522305
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromat...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of ALR2 in rat lens assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of human recombinant ALR2 expressed in Escherichia coli using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of ALR2 in rat sciatic nerve assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chroma...More data for this Ligand-Target Pair