BDBM50522483 CHEMBL4468959

SMILES OC=O.NC(=N)c1ccc(NCc2nc(c[nH]2)-c2ccccc2)cc1OCC1CC1

InChI Key InChIKey=APPAOTHSGRJITR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522483   

TargetKallikrein-1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50522483(CHEMBL4468959)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of recombinant bovine enterokinase activated N-terminal His-tagged recombinant human KLK1 (19 to 262 residues) expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein-5(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50522483(CHEMBL4468959)
Affinity DataIC50:  794nMAssay Description:Inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected Sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed