BDBM50525172 CHEMBL4443701
SMILES COc1cc2CCN(C=O)[C@@H](CCc3c[nH]c4cc(C)ccc34)c2cc1OCC1CC1
InChI Key InChIKey=ADOIAAOBUDGHPM-DEOSSOPVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50525172
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Shanghai Institute of Materia Medica
Curated by ChEMBL
Shanghai Institute of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human PDE4D catalytic domain using [3H]cAMP as substrate measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Shanghai Institute of Materia Medica
Curated by ChEMBL
Shanghai Institute of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of PDE4 in human PBMC assessed as reduction in LPS-stimulated TNFalpha production preincubated for 1 hr followed by LPS stimulation and me...More data for this Ligand-Target Pair