BDBM50525172 CHEMBL4443701

SMILES COc1cc2CCN(C=O)[C@@H](CCc3c[nH]c4cc(C)ccc34)c2cc1OCC1CC1

InChI Key InChIKey=ADOIAAOBUDGHPM-DEOSSOPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525172   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50525172(CHEMBL4443701)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant human PDE4D catalytic domain using [3H]cAMP as substrate measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50525172(CHEMBL4443701)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of PDE4 in human PBMC assessed as reduction in LPS-stimulated TNFalpha production preincubated for 1 hr followed by LPS stimulation and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed