BDBM50525176 CHEMBL4466435

SMILES COc1cc2CCN(C=O)[C@@H](Cc3c[nH]c4ccccc34)c2cc1OC

InChI Key InChIKey=KJLYODHJNMBXRK-IBGZPJMESA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525176   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50525176(CHEMBL4466435)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant human PDE4D (83 to 416 residues) expressed in Escherichia coli BL21 (DE3) assessed as hydrolysis of [3H]-cAMP measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50525176(CHEMBL4466435)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant human PDE4D catalytic domain using [3H]cAMP as substrate measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)