BDBM50527927 CHEMBL4436648

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cncc(\C=C2/SC(=N)NC2=O)c1

InChI Key InChIKey=AGHDPPGOJJYURV-AUWJEWJLSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50527927   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527927(CHEMBL4436648)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human PI5P4IKgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Homo sapiens)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527927(CHEMBL4436648)
Affinity DataIC50:  270nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527927(CHEMBL4436648)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed