BDBM50529166 CHEMBL4557047

SMILES Cc1ccc2SC(=S)N3CCCN=C3c2c1

InChI Key InChIKey=VEXIKOBXIPCAHQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50529166   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 residues) expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC5 expressed in baculovirus infected Sf9 cells using Boc-Lys(TFA)-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50:  57nMAssay Description:Inhibition of recombinant human full length N-terminal His6/SUMO-tagged HDAC8 expressed in Escherichia coli BL21 DE3 using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant human N-terminal His6/SUMO-tagged/C-terminal SII-tagged HDAC4 expressed in Escherichia coli BL21 DE3 using Boc-Lys(TFA)-AMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529166(CHEMBL4557047)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed