BDBM50530284 CHEMBL4590544
SMILES Clc1ccc(cc1Cl)-n1ccc(NC(=O)CC#N)n1
InChI Key InChIKey=ZZHVSXAXUYZGQM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50530284
Affinity DataIC50: 2.51E+3nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Affinity DataEC50: 7.94E+3nMAssay Description:Induction of human c-ABL phosphorylation at Y245/Y412 residues in bacmam-induced HEK-MSR2 cell lysates by in-cell Western blot analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 7.94E+3nMAssay Description:Induction of human c-ABL phosphorylation at Y245/Y412 residues in bacmam-induced HEK-MSR2 cell lysates by in-cell Western blot analysisMore data for this Ligand-Target Pair