BDBM50533261 CHEMBL4466010
SMILES COc1cc(ccc1CN)C(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H]1C[C@H]1c1ccccc1)n1cc(nn1)C1CC1
InChI Key InChIKey=WACYIZDLHZRJIP-UCKMRUJXSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50533261
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cells measured after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human PRSS1 assessed as enzymatic cleavage of Benzoyl-GlyPro-Arg'Rh110-gammaGlu-OH by fluorescence analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cells measured after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human PRSS1 assessed as enzymatic cleavage of Benzoyl-GlyPro-Arg'Rh110-gammaGlu-OH by fluorescence analysisMore data for this Ligand-Target Pair