BDBM50547857 CHEMBL4792173
SMILES Cc1[nH]c(C(=O)Nc2ccc3nc(NC(=O)C(O)=O)sc3c2)c(Cl)c1Cl
InChI Key InChIKey=QOIXLMNVJYVPLA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50547857
Affinity DataIC50: 29nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair