BDBM50555147 CHEMBL4748886
SMILES Cl.Cl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3CCCCC3C(=O)NCCN)cc2Cl)cccc1-c1ccccc1
InChI Key InChIKey=OUADRWVTCFSKMB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50555147
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of PD-1/PDL1 (unknown origin) measured after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataKd: 88nMAssay Description:Binding affinity to human PD-L1 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 47nMAssay Description:Binding affinity to mouse PD-L1 by surface plasmon resonanceMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataKd: 202nMAssay Description:Binding affinity to human PD-L1 by surface plasmon resonanceMore data for this Ligand-Target Pair
Affinity DataKd: 174nMAssay Description:Binding affinity to mouse PD-L1 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair