BDBM50568724 CHEMBL4850231

SMILES COc1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O

InChI Key InChIKey=WWSSIVALOHLUTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568724   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568724(CHEMBL4850231)
Affinity DataIC50:  44nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568724(CHEMBL4850231)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed