BDBM50577625 CHEMBL4847175

SMILES [2H]C([2H])([2H])N1CC[C@@H](C1)NC(=O)c1cc(cs1)-n1ncc2cc(Nc3ccccc3Cl)c(F)cc12

InChI Key InChIKey=VYNVVWLFRMWZRV-VSLDJYOXSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50577625   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577625(CHEMBL4847175)
Affinity DataIC50:  5nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577625(CHEMBL4847175)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by automated Qpatch electrophysiological methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577625(CHEMBL4847175)
Affinity DataIC50:  300nMAssay Description:Inhibition of p38 alpha (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577625(CHEMBL4847175)
Affinity DataIC50:  285nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed