BDBM50578733 CHEMBL4875851

SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cc(ccc1Cl)-c1ccc(cc1C)C(O)=O)C(F)(F)F)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QTXRBYGCEKYZNF-ADKRDUOOSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50578733   

TargetCholesteryl ester transfer protein(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataEC50: >3.00E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of [S35]-MK-0499 binding to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed