BDBM50579188 CHEMBL4874893
SMILES Cc1ccccc1-c1cc(Nc2ccnc3cc(ccc23)-c2ccc(cc2)S(C)(=O)=O)ccn1
InChI Key InChIKey=JKAPZPMQKNTGJW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50579188
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 358nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 expressed in baculovirus expression system using 5-FAM-KRELVEPLTPSGEAPNQALLR-CONH2 substrate preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair