BDBM50579188 CHEMBL4874893

SMILES Cc1ccccc1-c1cc(Nc2ccnc3cc(ccc23)-c2ccc(cc2)S(C)(=O)=O)ccn1

InChI Key InChIKey=JKAPZPMQKNTGJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579188   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579188(CHEMBL4874893)
Affinity DataIC50:  358nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 expressed in baculovirus expression system using 5-FAM-KRELVEPLTPSGEAPNQALLR-CONH2 substrate preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579188(CHEMBL4874893)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed