BDBM50582232 CHEMBL5091603

SMILES COC[C@H](C(=O)NCC(F)(F)F)c1ccc2[nH]c(nc2c1F)[C@@H](NC(=O)c1nonc1C1CC1)C1CCC(F)(F)CC1

InChI Key InChIKey=QJQOJBLTLRWCIE-KXBFYZLASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582232   

TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582232(CHEMBL5091603)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed