BDBM50582258 CHEMBL5094640

SMILES [H][C@@]12C[C@@]([H])(C=C1)[C@@H]([C@@H]2Nc1nc(Nc2cccc(c2)C(=O)N2CCCC2)ncc1-c1ccnc(F)c1)C(N)=O

InChI Key InChIKey=FLZAOAIEJUXTAH-HJOCRKTISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582258   

TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50582258(CHEMBL5094640)
Affinity DataIC50:  17nMAssay Description:Inhibition of TAK1 (unknown origin) in presence of MBP as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50582258(CHEMBL5094640)
Affinity DataIC50:  3nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of MBP as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed