BDBM50591148 CHEMBL5180390::US20240034730, Compound 19
SMILES Oc1nn2ccccc2c1C(=O)Nc1ccc2[nH]ccc2c1
InChI Key InChIKey=KJYSLOCSHRXONG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50591148
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair