BDBM50591148 CHEMBL5180390::US20240034730, Compound 19

SMILES Oc1nn2ccccc2c1C(=O)Nc1ccc2[nH]ccc2c1

InChI Key InChIKey=KJYSLOCSHRXONG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591148   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591148(CHEMBL5180390 | US20240034730, Compound 19)
Affinity DataIC50: >1.00E+4nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591148(CHEMBL5180390 | US20240034730, Compound 19)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed