BDBM50591323 CHEMBL5173239

SMILES CN1CC[C@H](C1)Oc1ccc(Cl)c(-c2nc3c(o2)C(=O)c2ccccc2C3=O)c1F

InChI Key InChIKey=WQSSCHGAVXKWEO-LLVKDONJSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50591323   

TargetUbiquitin thioesterase OTUB1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of N-terminal His-6 tagged OTUB1 (40 to 271 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Ub-Rho measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells measured after 3 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of USP1 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtaxin-3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ataxin-3 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of USP36 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed