BDBM50597526 CHEMBL5187166

SMILES CC(C#C)N(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=OUPIKZKLVSUKAU-FWMLXHAGSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597526   

TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597526(CHEMBL5187166)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597526(CHEMBL5187166)
Affinity DataKd:  8.10E+3nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed