BDBM50598016 CHEMBL5170047
SMILES COC(=O)c1cc(O)c2cc(NC(=O)NCCCCNC(=N)NC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cnc4c(N)ncnc34)ccc2c1
InChI Key InChIKey=AUWUXQSTBMRGEC-PTGPVQHPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50598016
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT1 (2 to 371 residues) using histone H4 as substrate incubated for 20 mins in presence of [...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of human full length recombinant GST his-tagged PRMT3 (2 to 531 residues) using histone H4 as substrate incubated for 20 mins in presence ...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT4 (2 to 608 residues) using histone H3 as substrate incubated for 20 mins in presence of [...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataKd: 2.30E+3nMAssay Description:Binding affinity to full length recombinant PRMT4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT6 (2 to 375 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT8 (61 to 394 residues) using histone H4 as substrate incubated for 20 mins in presence of ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 7.67E+4nMAssay Description:Inhibition of human full length recombinant FLAG-tagged PRMT5 (2 to 637 residues) using histone H2A as substrate incubated for 20 mins in presence of...More data for this Ligand-Target Pair