BDBM50601806 CHEMBL5204388

SMILES CN(C)C(=O)[C@H]1CCC[C@H](C1)c1cccc(c1)-n1ncc(C(O)=O)c1C1CC1

InChI Key InChIKey=YNOQXOCLOKUMBJ-WBVHZDCISA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601806   

TargetKelch-like ECH-associated protein 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50601806(CHEMBL5204388)
Affinity DataIC50:  240nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50601806(CHEMBL5204388)
Affinity DataEC50:  1.70E+3nMAssay Description:Induction of Nrf2 in human BEAS-2B cells assessed as increase in NQO1 protein level incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50601806(CHEMBL5204388)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed