BDBM50609879 CHEMBL5271406
SMILES CC1(C)\C(=C/C=C/C=C/C2=[N+](CCCCCC(=O)NCCCCCCCCN3CCC(CC3)OC(=O)Nc3ccc(F)cc3-c3ccc(F)c(Cl)c3)c3ccc(cc3C2(C)C)S([O-])(=O)=O)N(CCCCS(O)(=O)=O)c2ccccc12
InChI Key InChIKey=BMNOFIWIZFZYES-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50609879
Affinity DataKi: 0.140nMAssay Description:Displacement of tiotropium bromide from human muscarinic M3 receptor expressed in CHO cells incubated for 4 hrs by flow cytometric competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M4 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of atropine from human muscarinic M3 receptor expressed in CHO cells incubated for 2 hrs by flow cytometric competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M5 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to saturated human muscarinic M1 expressed in CHO cells assessed as dissociation constant incubated for 2 hrs by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:Binding affinity to saturated human muscarinic M1 expressed in CHO cells assessed as dissociation constant incubated for 2 hrs in presence of atropin...More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to saturated human muscarinic M3 expressed in CHO cells assessed as dissociation constant incubated for 2 hrs in presence of atropin...More data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding affinity to saturated human muscarinic M3 expressed in CHO cells assessed as dissociation constant incubated for 2 hrs by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Binding affinity to human muscarinic M3 receptor expressed in human HEK293T cells assessed as inhibition of carbachol-induced G-protein signaling by ...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Binding affinity to human muscarinic M3 receptor expressed in human HEK293T cells cells co-expressing beta-arrestin2 assessed as inhibition of carbac...More data for this Ligand-Target Pair