BDBM50610353 CHEMBL5270898
SMILES Cc1cc(nc(n1)N1CCCC1)N1CCN(CC1)C(=O)c1ccc(cc1)C(C)(C)C
InChI Key InChIKey=QJZSBJRVAIZDFO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50610353
Affinity DataEC50: 9.60nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of GCase in patient derived fibroblast cells using 5'pentafluorobenzoylaminofluorescein-di-beta-D-glucoside as substrate assessed as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant GCase (unknown origin) using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at pH 4.5More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell assessed as GCase level incubated for 5 days by immunocytochemistry a...More data for this Ligand-Target Pair