BDBM50659607 CHEMBL5395490

SMILES O=C(NCc1cccnc1)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccc(F)cc1

InChI Key InChIKey=FCUDWGSHVIZNIL-UHFFFAOYSA-N

Data  4 KI  5 Kd

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50659607   

TargetPeptidyl-prolyl cis-trans isomerase(Burkholderia pseudomallei (strain K96243))
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKd:  19nMAssay Description:Displacement of fluorescein-labeled tracer from TEV cleavable N-terminal His6-tagged Burkholderia pseudomallei MIP expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeptidyl-prolyl cis-trans isomerase(Burkholderia pseudomallei (strain K96243))
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKi:  90nMAssay Description:Inhibition of TEV cleavable N-terminal His6-tagged Burkholderia pseudomallei MIP expressed in Escherichia coli BL21 gold (DE3) cells using succinyl-A...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage infectivity potentiator(Trypanosoma cruzi)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKd:  467nMAssay Description:Displacement of fluorescein-labeled tracer from Ulp1 cleavable N-terminal His6/SUMO-tagged Trypanosoma cruzi MIP expressed in Escherichia coli BL21 g...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage infectivity potentiator(Trypanosoma cruzi)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Ulp1 cleavable N-terminal His6/SUMO-tagged Trypanosoma cruzi MIP expressed in Escherichia coli BL21 gold (DE3) cells using succinyl-Ala...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetOuter membrane protein MIP(Legionella pneumophila)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of TEV cleavable N-terminal His6-tagged Legionella pneumophila MIP (1 to 213 residues) expressed in Escherichia coli BL21 gold (DE3) cells...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOuter membrane protein MIP(Legionella pneumophila)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKd:  3.30E+3nMAssay Description:Displacement of TEV cleavable N-terminal His6-tagged truncated Legionella pneumophila MIP (77 to 213 residues) expressed in Escherichia coli BL21 gol...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOuter membrane protein MIP(Legionella pneumophila)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of TEV cleavable N-terminal His6-tagged truncated Legionella pneumophila MIP (77 to 213 residues) expressed in Escherichia coli BL21 gold ...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOuter membrane protein MIP(Legionella pneumophila)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKd:  4.70E+3nMAssay Description:Displacement of TEV cleavable N-terminal His6-tagged Legionella pneumophila MIP (1 to 213 residues) expressed in Escherichia coli BL21 gold (DE3) cel...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOuter membrane protein MIP(Legionella pneumophila)
Friedrich Schiller University Jena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659607BDBM50659607(CHEMBL5395490)
Affinity DataKd:  3.35E+4nMAssay Description:Displacement of TEV cleavable N-terminal His6-tagged truncated Legionella pneumophila MIP (100 to 213 residues) expressed in Escherichia coli BL21 go...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed