BDBM509672 US11364246, Example 23.15::US20200361871A1, Example 23.15

SMILES Clc1ccccc1CC(=O)Nc1ccnc(c1)C(=O)NC1(CCOCC1)C#N

InChI Key InChIKey=LMRLNQXCNVNKRZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509672   

TargetAnoctamin-1(Human)
Tmem16A

US Patent
LigandChemical structure of BindingDB Monomer ID 509672BDBM509672(US20200361871A1, Example 23.15 | US11364246, Examp...)
Affinity DataEC50:  1.19E+3nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetAnoctamin-1(Human)
Tmem16A

US Patent
LigandChemical structure of BindingDB Monomer ID 509672BDBM509672(US20200361871A1, Example 23.15 | US11364246, Examp...)
Affinity DataEC50:  1.19E+3nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent