BDBM510840 4-({(aR)-6-[6-(2- hydroxy-2- methylpropoxy)pyrazolo [1,5-a]pyridine- 3-amido]spiro[3.3] heptan-2-yl}oxy)-2- phenyl-1,3-thiazole- 5-carboxamide::US11078197, Example 17::US11673886, Example 17
SMILES CC(C)(O)COc1ccc2c(cnn2c1)C(=O)N[C@H]1C[C@]2(C1)C[C@@H](C2)Oc1nc(sc1C(N)=O)-c1ccccc1
InChI Key InChIKey=LRDAQXGTMOUYGH-YSDGCRRSSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510840
Affinity DataIC50: 18.5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair