BDBM510865 1-(difluoromethyl)- 6-(2-hydroxy-2- methylpropoxy)-N- [(aR)-6-[(4-carbamoyl-1- phenyl-1H-pyrazol-3- yl)oxy]spiro[3.3] heptan-2-yl]-1H- indazole-3- carboxamide::US11078197, Example 42::US11673886, Example 42
SMILES CC(C)(O)COc1ccc2c(nn(C(F)F)c2c1)C(=O)N[C@H]1C[C@]2(C1)C[C@@H](C2)Oc1nn(cc1C(N)=O)-c1ccccc1
InChI Key InChIKey=TVVZCSKROKCEHQ-FSKXATTISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510865
Affinity DataIC50: 13.7nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair