BDBM510918 3-methyl-5-{[(aR)- 6-[6-(2-hydroxy-2- methylpropoxy) pyrazolo[1,5-a]pyridine- 3-amido]spiro[3.3] heptan-2- yl]oxy}thieno[3,2- b]pyridine-6- carboxamide::US11078197, Example 97::US11673886, Example 97

SMILES Cc1csc2cc(C(N)=O)c(O[C@H]3C[C@@]4(C[C@@H](C4)NC(=O)c4cnn5cc(OCC(C)(C)O)ccc45)C3)nc12

InChI Key InChIKey=VJUMLRMGMJACBI-KHKBPRLJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510918   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510918(3-methyl-5-{[(aR)- 6-[6-(2-hydroxy-2- methylpropox...)
Affinity DataIC50:  12nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510918(3-methyl-5-{[(aR)- 6-[6-(2-hydroxy-2- methylpropox...)
Affinity DataIC50:  1.20E+4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent