BDBM510924 6-fluoro-N-[(aR)-6- ({5-carbamoyl-1- methyl-1H- pyrazolo[3,4- b]pyridin-6- yl}oxy)spiro[3.3] heptan-2-yl]quinoline- 3-carboxamide::US11078197, Example 103::US11673886, Example 103
SMILES Cn1ncc2cc(C(N)=O)c(O[C@H]3C[C@@]4(C[C@@H](C4)NC(=O)c4cnc5ccc(F)cc5c4)C3)nc12
InChI Key InChIKey=CMJDHSYRDWEFNM-RPPIVITFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510924
Affinity DataIC50: 5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair