BDBM517310 3-[3-(difluoromethoxy)phenyl]-1- (5-fluoropyridin-2-yl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen-3-yl)- 1H-indazole-6-carboxamide (enantiomer A)::US11104690, Example 128-A

SMILES C[C@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cn3)c2c1)-c1cccc(OC(F)F)c1

InChI Key InChIKey=NKGNVRFBFMKXKW-RUZDIDTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517310   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517310(3-[3-(difluoromethoxy)phenyl]-1- (5-fluoropyridin-...)
Affinity DataIC50:  3.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent