BDBM531693 (�)-N-[1-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]-6-{4-[1-methoxyethyl]-3,5-dimethyl-1H-pyrazol-1-yl}pyrimidin-4-amine (Racemic)::US11208400, Example 326::US11208400, Example 327::US11208400, Example 328

SMILES O=C1CCC(N2Cc3cc(CCCN4CCN(Cc5ccccc5-c5ccc(Cl)cc5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=RKHBQGNWTZMHMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531693   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531693BDBM531693(3-(5-(3-(4-((4'-chloro-[1,1'-biphenyl]-2- yl)methy...)
Affinity DataIC50: 1.15E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent