BDBM536170 N-((2S)-1-((4R)-2-(5-(4-Bromophenyl)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)-4-hydroxypyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)acetamide::US11242344, Example 101.1

SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(Br)cc1)C(C)(C)C

InChI Key InChIKey=BXQUIQWJTNLTHH-SVQXRNPESA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536170   

LigandPNGBDBM536170(N-((2S)-1-((4R)-2-(5-(4-Bromophenyl)-5-methyl-4-ox...)
Affinity DataKd: >5.00E+5nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM536170(N-((2S)-1-((4R)-2-(5-(4-Bromophenyl)-5-methyl-4-ox...)
Affinity DataIC50: >2.00E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent