BDBM543459 US11279699, Compound Example 10

SMILES O=C(Nc1nc2c(cccn2n1)-c1ccc(CN2CC(C2)S(=O)(=O)C2CC2)cc1)C1CC1

InChI Key InChIKey=VJDVFMNYDPUCOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 543459   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543459(US11279699, Compound Example 10)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543459(US11279699, Compound Example 10)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543459(US11279699, Compound Example 10)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent