BDBM543461 US11279699, Compound Example 12

SMILES CC(C)C(=O)Nc1nc2c(cccn2n1)-c1ccc(CN2CC(C2)S(C)(=O)=O)cc1

InChI Key InChIKey=AKELOESAQAKJRE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 543461   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543461(US11279699, Compound Example 12)
Affinity DataIC50:  35nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543461(US11279699, Compound Example 12)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543461(US11279699, Compound Example 12)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent