BDBM551476 (R)-1-(4-(3-(5-amino-9-fluoro-8-methoxy-[1,2,4]triazolo[1,5-c] quinazolin-2-yl)piperidin-1-yl)-3-cyclopropyl- 1H-pyrazol-1-yl)-2-methylpropan-2-ol::US11312719, Example 21
SMILES COc1cc2nc(N)n3nc(nc3c2cc1F)[C@@H]1CCCN(C1)c1cn(CC(C)(C)O)nc1C1CC1
InChI Key InChIKey=VFKMIEMLJHHTFK-OAHLLOKOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 551476
Affinity DataIC50: 515nMAssay Description:The reported affinity of the compounds of the invention for the human A2b adenosine receptor was determined experimentally using a radioligand filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test compound) were...More data for this Ligand-Target Pair