BDBM552638 WO2022101377, Example 37
SMILES Cc1nnc2CN[C@H](c3c4C[C@@H](Cc4sc3-n12)C(=O)NCc1cc(ccn1)C(F)(F)F)c1ccccc1Cl
InChI Key InChIKey=IXTPXSRECPDALL-PSLXWICFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 552638
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Boehringer Ingelheim International
WIPO
Boehringer Ingelheim International
WIPO
Affinity DataIC50: 2.90nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair