BDBM554133 US11325921, Example 20

SMILES FC(F)(F)Cc1cc2c(N3CC4(CN(C4)C(=O)[C@H]4N[C@@H]5CC[C@H]4C5)C3)c(cnc2s1)C#N

InChI Key InChIKey=ZYADRCWVQPCKIY-QEORTHHSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554133   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM554133(US11325921, Example 20)
Affinity DataIC50:  11.4nMAssay Description:Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent